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Exploring the Power of Kambo Peptides

In the heart of the Amazon rainforest lives the magical Phyllomedusa bicolor tree frog. Widely used by many people all over the world for a multitude of reasons. But what secrets lie within this mystical elixir? In this blog we will venture into the depths of Kambo peptides, where science and nature intertwine to unveil a world of healing potential.



Kambo secretion, far from being a tool for predation, despite popular belief that Kambo is a poison it more accurately has been shown to be a shield against the relentless Amazonian sun. It's not merely a defense mechanism but rather a sunscreen, safeguarding the frog's delicate skin during dry seasons.


At the core of Kambo's potency lies a rich tapestry of peptides and alkaloids. These peptides, (short chains of amino acids), hold the key to unlocking Kambo's medicinal potential. They bind to specific receptors within the body, orchestrating biological functions with finesse and precision.


Kambo peptides engage with cell receptors, ushering in natural and harmonious biological changes. From regulating mood and pain through endorphins to contributing to vital cellular processes, these peptides wield a symphony of effects within our physiology.


Within Kambo's embrace lie neuropeptides, molecular messengers within our nervous system. They modulate synaptic activity, regulate physiological processes, and shape our experiences, from pain perception and mood regulation to appetite and stress response.

Bio-active peptides emerge as versatile entities, wielding antimicrobial, antioxidant, antihypertensive, immunomodulatory, and anti-inflammatory activities. Sourced from various origins, including animal secretions like Kambo, they hold promise for diverse therapeutic applications.



Ongoing research delves into the potential medical applications of Kambo peptides, from alleviating depression and migraines to tackling blood circulation problems, organ diseases, and even cancer. Kambo's antimicrobial peptides stand as formidable warriors against drug-resistant strains, hinting at novel therapeutic approaches.


Dermorphin, Phyllomedusin, Caerulein, Adenoregulin, Dermaseptins, Phyllokinin, and Tryptophyllin - each peptide in Kambo's arsenal holds unique potential. From potent opioid analgesics to vasodilators, anti-inflammatories, and antioxidants, they paint a picture of nature's pharmacopeia at its finest.


Intrathecal administration of Kambo peptides is showing promising potential for effective pain relief, particularly for severe chronic cancer or postoperative pain. As we chart new routes in medicine, Kambo peptides may hold the key to a healthier, more vibrant future.

Dermaseptin B2 is for me the most interesting of the peptides as it emerges as a potent warrior in the fight against cancer, hindering tumor growth, curtailing blood vessel formation, and inducing cellular damage. While further research is warranted, Dermaseptin B2 shines as a beacon of hope in the realm of cancer treatment.

As we journey deeper into the realms of Kambo peptides, we find ourselves on the precipice of a new frontier in medicine. With nature as our guide and science as our compass, the secrets of Kambo may one day unlock the doors to a healthier, more vibrant future for us all.


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  • What is Kambo?
    Kambo is a secretion from the giant monkey frog (Phyllomedusa bicolor), traditionally used by the indigenous Matsés tribe of the Amazon. It is applied to small burns on the skin, allowing its bioactive peptides to enter the lymphatic system.
  • How do I register for KPA training?
    Check our 'Training' page and submit an application online.
  • What are the benefits of Kambo?
    Kambo is known for its detoxifying, immune-boosting, and energetic-clearing properties. Practitioners and clients report benefits such as: - Physical detoxification and system reset - Mental clarity and emotional release - Increased energy and resilience - Support for immune and endocrine health However, Kambo is not a medical treatment and should not be used as a cure for specific medical conditions.
  • Is Kambo safe?
    Yes, when administered by a trained and experienced practitioner, Kambo is generally safe. However, it is not suitable for everyone. Certain contraindications, such as heart conditions, severe blood pressure issues, and pregnancy, must be considered. A full health screening is required before receiving Kambo.
  • What is the Kambo Practitioner Alliance (KPA)?
    The Kambo Practitioner Alliance (KPA) is a global network of highly trained Kambo practitioners dedicated to safety, integrity, and ethical practice. KPA provides: - World-class training in Kambo application - A supportive community of practitioners - Continued learning opportunities
  • Why train with KPA?
    Authenticity & Indigenous Connection – KPA works directly with the Matsés tribe, ensuring ethical sourcing and preservation of traditional knowledge. - High Standards & Ethical Practice – Training is based on safety, integrity, and respect for the medicine. - Comprehensive Education – Covering not just Kambo application but also energetic awareness, deep client care, and practitioner responsibility. - Experienced Teaching – Led by Lewis Powell, a master practitioner with years of experience and a direct connection to the Matsés. - A Global Network – Be part of an international alliance of skilled practitioners.
  • Do I need prior experience to train as a Kambo practitioner?
    While no prior training is required, experience receiving Kambo is highly recommended. This ensures that students have a personal understanding of the medicine before learning to facilitate sessions for others.
  • What does KPA Practitioner Training include?
    Our comprehensive training program covers: - The science and safety of Kambo - Application techniques & safety protocols - Advanced spiritual & energetic practices - Practitioner ethics, holding space and boundaries - Trauma-informed care & emotional integration
  • How long does the training take?
    The standard Kambo Practitioner training runs for 10-12 days, with an emphasis on practical experience, assessments, and mentorship.
  • Where can I take a Kambo Practitioner training course?
    KPA offers training worldwide, including: - UK – London, Liverpool, Belfast, Scotland - Costa Rica - Peru (Matsés Amazon Expedition) - Other international locations Check our Training Schedule for upcoming courses.
  • What can I do with my certification after completing training?
    After completing training, practitioners are equipped to: - Offer private Kambo sessions - Host group ceremonies and retreats - Integrate Kambo into healing, wellness, or holistic practices - Join the KPA network for continued support and opportunities
  • Can I train others in Kambo after becoming a practitioner?
    No, only KPA Master Practitioners and Teachers are qualified to train others. If you are interested in teaching, you must first complete: - Advanced Kambo training - The KPA Teacher Training Program
  • Who should NOT receive Kambo? (Contraindications)
    Kambo is not safe for individuals with: - Heart conditions - Severe blood pressure issues - Stroke history - Epilepsy - Organ transplants - Pregnancy & breastfeeding - Certain mental health conditions (e.g., psychosis, bipolar disorder) A detailed health screening is required before treatment.
  • How do I prepare for a Kambo session?
    To prepare for a session: - Fast (no food 6-8 hours before) - Hydrate properly (avoid excessive water intake before) - Avoid alcohol & drugs (48 hours before & after) - Set an intention for your healing process Your practitioner will provide specific preparation and aftercare guidance.
  • What happens during a Kambo session?
    A typical Kambo session involves: - Health screening & intention setting - Application of small burns (gates) on the skin - Kambo application & immediate effects (flushing, purging, sweating) - Rest & integration after the purge Sessions last 30-40 minutes, with post-session grounding and support.
  • What are the possible side effects of Kambo?
    Short-term side effects may include: - Increased heart rate - Flushing or sweating - Dizziness or fainting - Nausea and purging These effects typically last 15-30 minutes, followed by a period of deep rest and clarity.
  • How often should I receive Kambo?
    This depends on your individual needs. Some receive one session for detox, while others benefit from a series of treatments (e.g., three sessions over a lunar cycle). Your practitioner can advise on a protocol suited to your goals.
  • Where does the Kambo used in KPA training come from?
    KPA works directly with the Matsés tribe of the Amazon, ensuring: - Fair trade & reciprocity with indigenous communities - Respectful and sustainable collection of Kambo - Authenticity in traditional medicine practices
  • How does KPA give back to the Matsés tribe?
    KPA actively supports the Matsés by: - Funding education and infrastructure projects - Providing medical and school supplies - Helping preserve their traditional medicine knowledge
  • How do I book a Kambo session with a KPA-trained practitioner?
    Visit our 'Find A Practitioner' page to find a certified KPA practitioner near you.
  • How do I contact KPA for more information?
    For general inquiries, email us at kambopractitioneralliance@gmail.com
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KAMBO PRACTITIONER ALLIANCE | 2025

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